IgG4 Autoimmune Disease Masquerading As Oroantral Fistula
نویسندگان
چکیده
IgG4-related disease (IgG4-RD) is an immune-mediated disorder that involves multiple organs and characterized by the infiltration of lymphoplasmacytic cells, including IgG4-positive plasma along with storiform fibrosis obliterative phlebitis in inflamed organs. The primary sites affected this condition include pancreas, bile ducts, salivary glands, aorta, lungs, kidneys, meninges, lacrimal mediastinal lymph nodes, retroperitoneum. pathogenesis linked to a type 2 T-helper-cell cytokine profile involvement regulatory T cells. However, exact mechanism still unknown. Patients are frequently misdiagnosed as having malignancies due resemblance lesions infections or other diseases certain tumors, such pancreatic cancer pseudo-renal pelvis tumor. Prompt identification essential delayed diagnosis until advanced stages can result severe organ damage potentially fatal outcomes, despite being highly responsive treatment. This report presents unusual case atypical presentation 38-year-old female patient. patient sought medical attention emergency department nasal septal erosions oral-antral fistula. Nasal cultures were conducted indicated presence Klebsiella ozaena. Subsequent investigations, biopsy, confirmed autoimmune disease.
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ژورنال
عنوان ژورنال: Cureus
سال: 2023
ISSN: ['2168-8184']
DOI: https://doi.org/10.7759/cureus.42475